陳文江，教授，蘭州大學(xué)哲學(xué)社會(huì)學(xué)院社會(huì)學(xué)系系主任，民族社會(huì)學(xué)博士生導(dǎo)師，社會(huì)學(xué)專業(yè)碩士研究生導(dǎo)師，長(zhǎng)期從事社會(huì)學(xué)理論和方法教學(xué)和研究。主要研究方向?yàn)槲鞑可鐣?huì)學(xué)、倫理學(xué)、民族社會(huì)學(xué)、道德社會(huì)學(xué)、文化社會(huì)學(xué)、社會(huì)研究方法，社會(huì)問題研究、社會(huì)性別研究、文化社會(huì)學(xué)研究。

蘭州大學(xué)研究生導(dǎo)師：畢玉蓉

　　學(xué)習(xí)經(jīng)歷

　　1996 香港中文大學(xué)生物系   博士

　　1985  蘭州大學(xué)生物系      碩士

　　1982  蘭州大學(xué)生物系      學(xué)士

　　工作經(jīng)歷

　　主要工作簡(jiǎn)歷:

　　02/1986-10/1988  蘭州大學(xué)生物系          助教

　　10/1988-01/1993  蘭州大學(xué)生物系          講師

　　02/1989-06/1989  中科院上海植生所        合作科研

　　02/1997-11/1997  香港中文大學(xué)生物化學(xué)系  訪問學(xué)者

　　11/1997-08/2000  蘭州大學(xué)生物學(xué)流動(dòng)站    工作

　　05/1999-12/2002  蘭州大學(xué)生命科學(xué)學(xué)院    副教授

　　07/2004–今    蘭州大學(xué)生命科學(xué)學(xué)院      教授

　　11/2003–今      蘭州大學(xué)生命科學(xué)學(xué)院    博士生導(dǎo)師

　　10/2000-03/2001  香港中文大學(xué)生物系      合作科研

　　07/2003-01/2004  香港科技大學(xué)生物系      合作科研

　　10/2004–今      蘭州大學(xué)生命科學(xué)學(xué)院    植物及植物生理研究所所長(zhǎng)

　　02/2007-11/2007  香港科技大學(xué)生物系      合作科研

　　教學(xué)及指導(dǎo)研究生情況

　　本科生課程：植物生理學(xué)；植物生理學(xué)實(shí)驗(yàn)

　　研究生課程：高級(jí)植物生理學(xué)；植物呼吸代謝

　　發(fā)表論文及專著

　　主要發(fā)表文章：

　　Ping Li, Chengzhou Zhao, Yongqiang Zhang, Xiaomin Wang, Jianfeng Wang, Feng Wang, Yurong Bi*, Silicon enhances the tolerance of Poa annua to cadmium by inhibiting its absorption and oxidative stress, Biol Plantarum 2017, 61 (4): 741-750.

　　Feng Wang, Xiaomin Wang, Chengzhou Zhao, Jianfeng Wang, Ping Li, Yanqin Dou, Yurong Bi*, Alternative pathway is involved in the tolerance of highland barley to the low-nitrogen stress by maintaining the cellular redox homeostasis, Plant Cell Report, 2016, 35: 317-328.

　　Chengzhou Zhao, Xiaomin Wang, Xiaoyu Wang, Kunlun Wu, Ping Li, Ning Chang, Jianfeng Wang, Feng Wang, Jiaolong Li, Yurong Bi*, Glucose-6-phosphate dehydrogenase and alternative oxidase are involved in the cross tolerance of highland barley to salt stress and UV-B radiation, Jounal of Plant Physiology, 2015, 181: 83-95.

　　Jianfeng Wang, Yongqiang Zhang, Ying Li, Xiaomin Wang, Wenbin Nan, Yanfeng Hu, Hong Zhang, Chengzhou Zhao, Feng Wang, Ping Li, Hongyong Shi, Yurong Bi*, Endophytic microbes Bacillus sp. LZR216-regulated root development is dependent on polar auxin transport in Arabidopsis seedlings, Plant Cell Report, 2015, 34(6): 1075-1087.

　　Ping Li, Chengzhou Zhao, Yongqiang Zhang, Xiaomin Wang, Xiaoyu Wang, Jianfeng Wang, Feng Wang, Yurong Bi*, Calcium alleviates cadmium-induced inhibition on root growth by maintaining auxin homeostasis in Arabidopsis seedlings, Protoplasma, 2015, 253(1): 185-200.

　　Xiaolei Liang, Huahua Wang, Yanfeng Hu, Lina Mao, Lili Sun, Tian Dong, Wenbin Nan, Yurong Bi*, Silicon does not mitigate cell death in cultured tobacco BY-2 cells subjected to salinity without ethylene emission, Plant Cell Report, 2015, 34: 331-343.

　　Wenbin Nan, Xiaomin Wang, Lei Yang, Yanfeng Hu, Yantao Wei, Xiaolei Liang, Lina Mao, Yurong Bi*i, Cyclic GMP is involved in auxin signalling during Arabidopsis root growth and development, Journal of Experimental Botany, 2014, 65:1571-1583.

　　Yanfeng Hu, Jiaolong Li, Lijing Yang, Wenbin Nan, Xiaoping Cao, Yurong Bi*, Inhibition of root growth by narciclasine is caused by DNA damage-induced cell cycle arrest in lettuce seedlings, Protoplasma, 2014, 251:1113–1124.

　　Xiaomin Wang, chen Hou, Jie Liu, Wenliang He, Huiling Gong, chengyuan Shi, Yurong Bi*, Hydrogen peroxide plays a role in the regulation of rice (Oryza sativa L.) tolerance to salt stress, Acta Physiologiae Plantarum, 2013, 35(3): 891-900.

　　Jie Liu, Xiaomin Wang, Yanfeng Hu, Wei Hu, Yurong Bi*, Glucose-6-Phosphate dehydrogenase plays a pivotal role in tolerance to drought stress in soybean roots, Plant Cell Report, 2013, 32: 415-429.

　　Lei Zhang, Jie Liu, Xiaomin Wang, Yurong Bi*i, Glucose-6-phosphate dehydrogenase cooperated act as a regulator of cell redox balance in rice suspension cells under salt stress, Plant Growth Regulation, 2013, 69: 139-148.

　　Yinggao Liu, Qi Wan, Ruru Wu, Xiaomin Wang, Yurong Bi*, Role of hydrogen peroxide in regulating glucose-6-phosphate dehydrogenase expression and activity under salt stress, Biol Plantarum, 2012, 56 (2): 313-320.

　　Huiling Gong, Guishen Chen, Fengjuan Li, Xiaomin Wang, Yanfeng Hu, Yurong Bi*, (2012) Involvement of G6PDH in regulation of heat stress tolerance in the calli from Przewalskia tangutica and tobacco, Biol Plantarum, 2012, 56(3): 422-430.

　　Yanfeng Hu, Lijing Yang, Xiaofan Na, Xiaolei Liang, Xiaomin Wang, Yurong Bi*, Narciclasine inhibits responses of Arabidopsis roots to auxin, Planta, 2012, 236: 597-612.

　　Xiaolei Liang, Huahua Wang, Lina Mao, Yanfeng Hu, Tian Dong, Yongqiang Zhang, Xiaomin Wang, Yurong Bi*, Involvement of COP1 in ethylene- and light-regulated hypocotyl elongation, Planta, 2012, 236: 1791-1802.

　　Hongxia Lu, Qi Wan, Huahua Wang, Xiaofan Na, Xiaomin Wang Yurong Bi**, Oxidative stress and mitochondrial dysfunctions are early events in narciclasine-induced programmed cell death in tobacco Bright Yellow-2 cells, Physiologia Plantarum 2012, 144: 48–58.

　　Jisheng Li, Xiaomin Wang, Yanli Zhang, Honglei Jia, Yurong Bi*, cGMP regulates hydrogen peroxide accumulation in calcium-dependent salt resistance pathway in Arabidopsis thaliana roots, Planta, 2011, 234: 709-722.

　　Zeyong Zhang, Huahua Wang, Xiaomin Wang, Yurong Bi*, Nitric oxide enhances aluminum tolerance by affecting cell wall polysaccharides in rice roots, Plant Cell Report, 2011, 30: 1701-1711.

　　Xiaofan Na, Yanfeng Hu, Kun Yue, Hongxia Lu, Pengfei Jia, Huahua Wang, Xiaomin Wang, Yurong Bi*, Narciclasine modulates polar auxin transport in Arabidopsis roots, Journal of Plant Physiology, 2011, 168(11): 1149-1156.

　　Xiaofan Na, Yanfeng Hu, Kun yue, Hongxia Lu, Pengfei Jia, Huahua Wang, Xiaomin Wang, Yurong Bi*, Narciclasine affects the coordination between cell division and differentiation in Arabidopsis root tip, BMC Plant Biology, 2011, 11: 184.

　　Yongqiang Zhang, Sheng Zheng, Zhongjuan Liu, Liguang Wang, Yurong Bi*, HY5 and HYH are both necessary regulators for low temperature-induced anthocyanin accumulation in Arabidopsis seedlings, Journal of Plant Physiology 2011, 168:367-374.

　　Yongqiang Zhang, Zhongjuan Liu, Rongzhi Liu, Liguang Wang, Yurong Bi*, Gibberellins negatively regulate light-induced nitrate reductase activity in Arabidopsis seedlings, Journal of Plant Physiology 2011, 168: 2161-2168.

　　Zhongjuan Liu, Yongqiang Zhang, Rongzhi Liu, Hualing Hao, Zhi Wang, Yurong Bi*, Phytochrome interacting factors (pifs) are necessary regulators for sucrose-induced hypocotyl elongation in Arabidopsis. Journal of Plant Physiology, Journal of Plant Physiology 2011, 168:1771-1779.

　　Huahua Wang, Junjun Huang, Xiaolei Liang, Yurong Bi*, Involvement of hydrogen peroxide, calcium and  ethylene  in  the  induction of  the alternative pathway in chilling-stressed Arabidopsis callus, Planta 2011, 235:53-67.

　　Xiao fan Na, Yanfeng Hu, Kun Yue, Hongxia Lu, Pengfei Jia, Huahua Wang, Xiaomin Wang, Yurong Bi*, Narciclasine affects the coordination between cell division and differentiation in Arabidopsis root tip, BMC Plant Biol 2011, 11:184.

　　Xiaomin Wang, Jisheng Li, Jie liu, Wenliang He, Yurong Bi*, Nitric oxide increases mitochondrial respiration in the cGMP-dependent manner in the callus from Arabidopsis, Nitric Oxide, 2010, 23: 242-250.

　　Lijun Ling, Yanzhuo Yang, Yurong Bi*, Expression and characterization of two domains of Pinellia ternate agglutinin (PTA), a plant agglutinin from Pinellia ternate with antifungal activity, World J Microbiol Biotechnol 2010, 26:545–554

　　Wang HH, Liang XL, Huang JJ, Zhang DK, Lu HX, Liu ZJ, Yurong Bi*, Involvement of ethylene and hydrogen peroxide in induction of alternative respiratory pathway in salt-treated Arabidopsis calluses, Plant Cell Physiol 2010, 51: 1754-1765

　　Yongqiang Zhang, Zhongjuan Liu, Liguang Wang, Sheng Zheng, Jiping Xie, Yurong Bi*, Sucrose-induced hypocotyl elongation of Arabidopsis seedlings in darkness depends on the presence of gibberellins. Journal of plant physiology 2010, 167(14):1130-1136

　　Huahua Wang, Xiaolei Liang, Qi Wan, Xiaomin Wang, Yurong Bi*, Ethylene and nitric oxide are involved in maintaining ion homeostasis in Arabidopsis callus under salt stress, Planta 2009, 230: 293-307

　　Xiaomin Wang, Yuanyuan Ma, Chenghong Huang, Qi Wan, Ning Li, Yurong Bi*, Glucose-6-phosphate dehydrogenase plays a central role in modulating reduced glutathione levels in reed callus under salt stress, Planta, 2008, 227:611-623.

　　Yingguao Liu, Ruru Wu, Qi Wan, Yurong Bi*, Glucose-6-phosphate dehydrogenase plays a pivotal role in nitric oxide-involved defense against oxidative stress under salt stress in red kidney bean roots, Plant Cell Physiollogy 2007,48:511-522

　　Mingguang Zhao, Yinggao Liu, Lixin Zhang, Lin Zhen, Yurong Bi*, Effects of enhanced UV-B radiation on the activity and expression of alternative oxidase in red kidney bean leaves, Journal of Integrative Plant Biol 2007, 49 (9): 1320–1326

　　研究方向

　　植物呼吸代謝, 植物抗性生理，植物化學(xué)及生物活性物質(zhì)的生理生化活性的研究。

　　項(xiàng)目成果

　　主持項(xiàng)目：

　　國(guó)家自然科學(xué)基金面上項(xiàng)目，“青稞AOX與G6PDH功能及其抗逆機(jī)理研究”，2017.01.01-2020.12.31，62萬

　　省、市、自治區(qū)科技項(xiàng)目“呼吸代謝在大豆抗旱適應(yīng)性中的調(diào)節(jié)機(jī)理與信號(hào)轉(zhuǎn)導(dǎo)研究”，2017.01.01-2020.12.31，10萬

　　蘭州市科技計(jì)劃項(xiàng)目，“促進(jìn)植物生長(zhǎng)內(nèi)生菌（PGPE）生物菌肥的研制及其對(duì)青稞生長(zhǎng)和品質(zhì)的影響”，2016.01.01-2017.12.31，10萬

　　甘肅省科技計(jì)劃項(xiàng)目，“冬小麥抗旱的生理與分子調(diào)控”，2013.11.01-2016.12.31，8萬

　　國(guó)家自然科學(xué)基金面上項(xiàng)目，“呼吸代謝在植物應(yīng)答和抵抗鹽脅迫中的作用機(jī)制研究”，2012.01.01-2015.12.31，55萬

　　甘肅省科技計(jì)劃項(xiàng)目，“青稞對(duì)環(huán)境脅迫的生理響應(yīng)及信號(hào)轉(zhuǎn)導(dǎo)與分子機(jī)理研究”，2012.01.01-2015.12.31，3萬

　　甘肅省科技計(jì)劃項(xiàng)目，“冬小麥抗旱評(píng)價(jià)體系建立及抗旱分子機(jī)理研究”，2012.09.01-2016.09.30，9萬

　　國(guó)家自然科學(xué)基金面上項(xiàng)目，“水仙生長(zhǎng)抑制物Narciclasine化感作用的生理與分子生物學(xué)研究”，2006.01.01-2009.12.31，28萬

　　教育部科技項(xiàng)目，“低溫誘導(dǎo)花青素積累依賴于光的分子機(jī)理研究”，2011.01.01-2013.12.31，6萬元

　　教育部科技項(xiàng)目，“G6PDH與NO在植物鹽脅迫響應(yīng)與信號(hào)傳導(dǎo)中的協(xié)同作用”，2006.01.01-2008.12.31，6萬元

　　榮譽(yù)、獲獎(jiǎng)

　　1. 《植物愈傷組織呼吸代謝研究》，獲1987年甘肅省科技 進(jìn)步三等獎(jiǎng)；

　　2. 《植物發(fā)育的物質(zhì)代謝與有關(guān)酶的調(diào)節(jié)研究》，分別獲 1990年甘肅省教委科技進(jìn)步一等獎(jiǎng)和甘肅省科委科技進(jìn)步二等獎(jiǎng)（6/6）；

　　3. 《植物呼吸代謝多條途經(jīng)運(yùn)行的調(diào)節(jié)及其生理意義》獲 1997年教育部科技步二等獎(jiǎng)（3/5）；

　　4. 《植物主要膜系統(tǒng)電子傳遞生理功能與活性調(diào)節(jié)》，獲 2004年教育部科技步二等獎(jiǎng)（11/11）；

　　5.  參加《植物生理學(xué)學(xué)習(xí)指導(dǎo)與題解》一書編寫，華中科技大學(xué)出版社，2003，2007年再版；

　　6.  2009年被評(píng)為蘭州大學(xué)“巾幗標(biāo)兵”。

 

蘭州大學(xué)研究生導(dǎo)師：邱全勝

　　學(xué)習(xí)經(jīng)歷

　　1981-1985    學(xué)士, 蘭州大學(xué)生物系植物生理專業(yè)

　　1985-1988    碩士, 蘭州大學(xué)生物系植物生理專業(yè)

　　1991-1994    博士, 蘭州大學(xué)生物系植物生理專業(yè)

　　1994-1996    博士后, 中科院生物物理所生物大分子國(guó)家重點(diǎn)實(shí)驗(yàn)室

　　2000-2009    博士后，University of Illinois，University of Arizona等

　　工作經(jīng)歷

　　2009-現(xiàn)在    教授, 博士生導(dǎo)師, 蘭州大學(xué)萃英特聘教授, 蘭州大學(xué)生命學(xué)院

　　1996-2000    副教授, 北京師范大學(xué)生命學(xué)院

　　1988-1994    助教, 講師, 蘭州大學(xué)生物系

　　教學(xué)及指導(dǎo)研究生情況

　　講授本科生專題課《植物蛋白組學(xué)概論》

　　講授研究生課程《植物蛋白組學(xué)研究進(jìn)展》

　　實(shí)驗(yàn)室現(xiàn)有博士研究生4名：鄭晟，王立光，武學(xué)霞，樊立剛。

　　實(shí)驗(yàn)室現(xiàn)有碩士研究生7名：潘婷，任玲，段育龍，趙雷，萬鵬，劉亞芬，袁亞鵬。

　　發(fā)表論文及專著

　　1. Qiu QS. V-ATPase, ScNhx1p and yeast vacuole fusion. JGG, 2012, 10.1016/j.jgg.2012.02.001

　　2. Qiu QS. Plant and yeast NHX antiporters: roles in membrane trafficking. J Integr Plant Biol, 2012, 54: 66–72

　　3. Sasser T, Qiu QS*, Karunakaran S, Padolina M, Reyes A, Flood B, Smith S, Gonzales C, Fratti RA.The yeast lipin 1 orthologue Pah1p regulates vacuole homeostasis and membrane fusion. J Biol Chem, 2012, 287: 2221–2236 (*Co-first author)

　　4. Qiu QS, Fratti RA.The Na+/H+ exchanger Nhx1p regulates the initiation of Saccharomyces cerevisiae vacuole fusion. J Cell Sci, 2010, 123: 3266-3275

　　5. Qiu QS, Huber JL, Booker FL, Jain V, Leakey A, Fiscus EL, Yau PM, Ort DR, Huber SC. Increased protein carbonylation in leaves of Arabidopsis and soybean in response to elevated [CO2] and [O3]. Photosyn Res, 2008, 97:155-66

　　6. Qiu QS, Hardin SC, Brutnell TP, Huber SC. Light and metabolic signals control the selective degradation of SUS in maize leaves during de-etiolation. Plant Physiol, 2007, 144: 468-478

　　7. Fuglsang AT, Guo Y, Cuin TA, Qiu QS, Song C, Kristiansen KA, Bych K, Schulz A, Shabala S, Schumaker KS, Palmgren MG, Zhu JK. Protein kinase PKS5 inhibits the plasma membrane H+-ATPase by preventing interaction with 14-3-3 protein. Plant Cell, 2007, 19:1617-34

　　8. Batelli G, Verslues PE, Agius F, Qiu QS, Fujii H, Pan S, Schumaker KS, Grillo S, Zhu JK. SOS2 promotes salt tolerance in part by interacting with the vacuolar H+-ATPase and upregulating its transport activity. Mol Cell Biol 2007, 27:7781-90

　　9. Qiu QS, Guo Y, Quintero FJ, Pardo JM, Schumaker KS, Zhu JK. Regulation of Vacuolar Na+/H+ Exchange in Arabidopsis thaliana by the Salt-Overly-Sensitive (SOS) Pathway. J Biol Chem, 2004, 279: 207.

　　10. Guo Y, Qiu QS, Quintero FJ, Pardo JM, Ohta M, Zhang C, Schumaker KS, Zhu JK. Transgenic Evaluation of Activated Mutant Alleles of SOS2 Reveals a Critical Requirement for Its Kinase Activity and C-Terminal Regulatory Domain for Salt Tolerance in Arabidopsis thaliana. Plant Cell, 2004, 16:435.

　　11. Song CP, Guo Y, Qiu QS, Lambert G, Galbraith DW, Jagendorf A, Zhu JK. A probable Na+(K+)/H+ exchanger on the chloroplast envelope functions in pH homeostasis and chloroplast development in Arabidopsis thaliana. Proc Natl Acad Sci U S A, 2004, 101, 10211.

　　12. Qiu QS, Vera-Estrella R, Barkla BJ, Zhu JK, Schumaker KS. Na+/H+ exchange activity in the plasma membrane of Arabidopsis thaliana. Plant Physiol, 2003,132 1041.

　　13. Qiu QS, Guo Y, Dietrich MA, Schumaker KS, Zhu JK. Regulation of SOS1, a plasma membrane Na+/H+ exchanger in Arabidopsis thaliana, by SOS2 and SOS3. Proc Natl Acad Sci U S A, 2002, 99, 8436.

　　14. Qiu QS, Zhang N. Water stress inhibited PNPP hydrolysis activity of the plasma membrane H+-ATPase from soybean hypocotyls. Australian J. Plant Physiol., 2000,27: 717

　　15. Qiu QS,Wang ZZ, Zhang N, Cai QG, Jiang RX. Aquaporins at the leaf callus protoplasts from Actinidia deliciosa var deliciosa cv. Hayward. Australian J. Plant Physiol., 2000,27:71

　　16. Qiu QS. Characterization of PNPP hydrolysis by plasma membrane H+-ATPases from soybean hypocotyls. J. Plant Physiol , 1999,154:628

　　17. Qiu QS, Su XF. The influence of extracellular side Ca2+  on the activity of the plasma membrane H+-ATPase from wheat roots. Australian J. Plant Physiol. 1998, 25(8):923

　　18. Qiu QS, Cheng P, Liang HG. Characterization of the NAD(P)H oxidation by purified plasma membrane vesicles using a spin-trapping EPR  method. J. Plant Physiol. 1995,146: 445

　　19. Qiu QS, Liang HG. Lipid peroxidation caused by the redox system of plasma membranes from wheat roots. J. Plant Physiol. 1995, 145: 261

　　20. Qiu QS, Liang HG, Zheng HJ, Cheng P. Ca2+-calmodulin-stimulated superoxide generation by purified plasma membrane from wheat roots. Plant Science, 1994,101: 99

　　研究方向

　　1.植物跨膜離子轉(zhuǎn)運(yùn):以擬南芥為模式植物，研究Na+(K+)/H+反向交換體離子轉(zhuǎn)運(yùn)的生化特性和調(diào)節(jié)機(jī)理及其在離子平衡，pH調(diào)節(jié)和植物耐鹽脅迫方面的生物學(xué)功能。

　　2.生物膜融合:以酵母和擬南芥為模式生物，研究膜微囊轉(zhuǎn)運(yùn)（vesicle trafficking）和生物膜融合（membrane fusion）的分子機(jī)理及其在信號(hào)轉(zhuǎn)導(dǎo)和蛋白質(zhì)分揀過程中的作用。

　　項(xiàng)目成果

　　榮譽(yù)、獲獎(jiǎng)

　　社會(huì)工作

　　2012-現(xiàn)在   《西北植物學(xué)報(bào)》編委

　　其它信息

蘭州大學(xué)研究生導(dǎo)師：茍小平

　　學(xué)習(xí)經(jīng)歷

　　1998.09-2001.07：四川大學(xué)生命科學(xué)學(xué)院植物學(xué)專業(yè)，理學(xué)博士

　　1995.09-1998.07：四川大學(xué)生命科學(xué)學(xué)院植物學(xué)專業(yè)，理學(xué)碩士

　　1991.09-1995.07：四川大學(xué)生物系植物學(xué)專業(yè)，理學(xué)學(xué)士

　　1998.09-2001.07:  Ph.D., Botany, College of Life Sciences, Sichuan University

　　1995.09-1998.07:  M.S., Botany, College of Life Sciences, Sichuan University

　　1991.09-1995.07:  B.S., Botany, Department of Biology, Sichuan University

　　工作經(jīng)歷

　　2009.10－目前：      蘭州大學(xué)萃英特聘教授，博士生導(dǎo)師，蘭州大學(xué)生命科學(xué)學(xué)院

　　2001.10－2009.09：博士后，The University of Oklahoma，USA

　　2009.10-Present:      Professor of plant biology, School of Life Sciences, Lanzhou University, China

　　2001.10-2009.9:       Postdoctoral research associate, Department of Microbiology and Plant Biology, University of Oklahoma, USA

　　教學(xué)及指導(dǎo)研究生情況

　　1、研究生招生（Masters and Ph.D. Programs）：

　　碩士研究生招生  專業(yè)：植物學(xué)（071001）；方向：植物分子生物學(xué)、植物分子發(fā)育生物學(xué)、植物細(xì)胞信號(hào)轉(zhuǎn)導(dǎo)

　　博士研究生招生  專業(yè)：植物學(xué)（071001）；方向：植物分子遺傳學(xué)、植物分子發(fā)育生物學(xué)、植物生殖生物學(xué)

　　目前指導(dǎo)博士研究生8人，碩士研究生6人。

　　歡迎報(bào)考博士、碩士研究生，合作開展博士后研究工作。

　　Major for master students: Plant Biology (Plant Molecular Biology, Plant Developmental Biology, Plant Cell Signaling)

　　Major for Ph.D. students: Plant Biology (Plant Molecular Genetics, Plant Developmental Biology, Plant Reproductive Biology)

　　2、教學(xué)（Teaching）：

　　植物生殖與發(fā)育生物學(xué)（秋季，本科生）／Plant Reproductive & Developmental Biology (Fall, Undergraduate)

　　植物生殖生物學(xué)（秋季，研究生）／Plant Reproductive Biology (Fall, Graduate)

　　分子克隆與基因工程（秋季，研究生）／Molecular Cloning & Genetic Engineering (Fall, Graduate)

　　本科生科研訓(xùn)練（本科生）／Independent Study Courses in Plant Biology (Spring/Fall, Undergraduate)

　　發(fā)表論文及專著

　　Du J, Gao Y, Zhan Y, Zhang S, Wu Y, Xiao Y, Zou Bo, He K, Gou X, Li G, Lin H, Li J. (2016). Nucleocytoplasmic trafficking is essential for BAK1 and BKK1-mediated cell-death control. Plant Journal, doi: 10.1111/tpj.13125.

　　Zhang J, Yuan T, Duan X, Wei X, Li J, Russell SD, Gou X. (2016). Cis-regulatory elements determine germline specificity and expression level of an isopentenyltransferase gene in sperm cells of Arabidopsis. Plant Physiology, doi:10.1104/pp.15.01510.

　　Yue J, Qin Q, Meng S, Jin H, Gou X, Li J, Hou S. (2016). TOPP4 regulates the stability of phytochrome interacting factor 5 during photomorphogenesis in Arabidopsis. Plant Physiology, doi:10.1104/pp.15.01729.

　　Wu Y, Xun Q, Guo Y, Zhang J, Cheng K, Shi T, He K, Hou S, Gou X, Li J. (2016) Genome-wide expression pattern analyses of the Arabidopsis leucine-rich repeat receptor-like kinases. Molelular Plant, 10.1016/j.molp.2015.12.011.

　　Shi T, Dimitrov I, Zhang Y, Tax FE, Yi J, Gou X, Li J. (2015). Accelerated rates of protein evolution in barley grain and pistil biased genes might be legacy of domestication. Plant Molecular Biology, 89: 253-261.

　　Anderson S, Johnson C, Jones D, Conrad L, Gou X, Russell SD, Sundaresan V. (2013). Transcriptomes of isolated rice gametes characterized by deep sequencing: Evidence for distinct sex-dependent chromatin and epigenetic states before fertilization. Plant Journal, 76: 729-741.

　　Russell SD, Gou X, Wong CE, Wang XK, Yuan T, Wei XP, Bhalla PL, Singh MB. (2012). Genomic profiling of rice sperm cell transcripts reveals conserved and distinct elements in the flowering plant male germ lineage. New Phytologist, 195: 560-573.

　　Du J, Yin H, Zhang S, Wei Z, Zhao B, Zhang J, Gou X, Lin H, Li J. (2012). Somatice embryogenesis receptor kinases control root development mainly via brassinosteroid-independent actions in Arabidopsis thaliana. Journal of Integrative Plant Biology, 54: 388-399.

　　Gou X, Li J. (2012). Activation tagging. Methods in Molecular Biology, 876. DOI: 10.1007/978-1-61779-809-2_9.

　　Gou X, Yin H, He K, Du J, Yi J, Xu S, Lin H, Clouse SD, Li J. (2012). Genetic evidence for an indispensable role of somatic embryogenesis receptor kinases in brassinosteroid signaling. PLoS Genetics, 8: e1002452.

　　Li J, Du J, He K, Gou X. (2011). Control of cell death by Receptor Kinases in Arabidopsis thaliana. In "Receptor-like Kinases in Plants: From Development to Defense (eds Birgit Kemmerling and Frans Tax)". Signaling and Communication in Plants (ed. Frantisek Baluska, Springer Publisher), Volume 13, pp79-91.

　　An J, Guo Z, Gou X, Li, J. (2011) TCP1 positively regulates the expression of DWF4 in Arabidopsis thaliana. Plant Signaling & Behavior, 6: 1117-1118.

　　Ge L, Gou X, Yuan T, Strout GW, Nakashima J, Blancaflor EB, Tian HQ, Russell SD. (2010). Migration of sperm cells during pollen tube elongation in Arabidopsis thaliana: behavior during transport, maturation and upon dissociation of male germ unit associations. Planta, 233:325-332.

　　Guo Z, Fujioka S, Blancaflor EB, Miao S, Gou X, Li J. (2010). TCP1 controls brassinosteroid biosynthesis by regulating the expression of the key biosynthetic gene DWARF4 in Arabidopsis thaliana. Plant Cell 22, 1161-1173.

　　Russell SD, Gou X, Wei X, Yuan T. (2010). Male gamete biology in flowering plants. Biochemical Society Transactions 38, 598-603.

　　Yang H, Gou X, He K, Xi D, Du J, Lin H, Li J. (2010). BAK1 and BKK1 in Arabidopsis thaliana confer reduced susceptibility to turnip crinkle virus. European Journal of Plant Pathology 127, 149-156.

　　Gou X, He K, Yang H, Yuan T, Clouse SD, Li J. (2010). Genome-wide cloning and sequence analysis of leucine-rich repeat receptor-like protein kinase genes in Arabidopsis thaliana. BMC Genomics 11, 19.

　　Gou X, Yuan T, Wei X, Russell SD. (2009). Gene expression in the dimorphic sperm cells of Plumbago zeylanica: Transcript profiling, diversity, and relationship to cell type. Plant Journal 60, 33-47.

　　He K, Gou X, Powell RA, Yang H, Yuan T, Guo Z, Li J. (2008). Receptor-like protein kinases, BAK1 and BKK1, regulate a light-dependent cell-death control pathway. Plant Signaling & Behavior 3: 813-815.

　　Li J, Gou X. (2007). Brassinosteroids. In Handbook of plant science (Roberts, K., ed). John Wiley & Sons, Ltd, pp. 395-404.

　　He K, Gou X, Yuan T, Lin H, Asami T, Yoshida S, Russell SD, Li J. (2007). BAK1 and BKK1 regulate brassinosteroid-dependent growth and brassinosteroid-independent cell-death pathways. Current Biology 17, 1109-1115.

　　Yuan T, Fujioka S, Takatsuto S, Matsumoto S, Gou X, He K, Russell SD, Li J. (2007). BEN1, a gene encoding a dihydroflavonol 4-reductase (DFR)-like protein, regulates the levels of brassinosteroids in Arabidopsis thaliana. Plant Journal 51, 220-233.

　　Wei X, Gou X, Yuan T, Russell SD. (2006). A highly efficient in vitro plant regeneration system and Agrobacterium-mediated transformation in Plumbago zeylanica. Plant Cell Rep 25, 513-521.

　　研究方向

　?。?）受體激酶介導(dǎo)的細(xì)胞信號(hào)轉(zhuǎn)導(dǎo)。受體激酶（RLKs）分布在細(xì)胞表面，從胞外環(huán)境獲取信號(hào)并傳遞到細(xì)胞內(nèi)啟動(dòng)下游的基因表達(dá)和調(diào)控，從而讓植物體對(duì)各種信號(hào)作出正確的反應(yīng)。在擬南芥中有600個(gè)以上的受體激酶，到目前為止只對(duì)其中很少一部分基因的功能有所了解。我們克隆了其中絕大部分受體激酶的全長(zhǎng)cDNA，并轉(zhuǎn)化野生型擬南芥進(jìn)行了超表達(dá)，目前正致力于解析這些受體激酶的生物學(xué)功能。

　　Functional Analysis of Receptor Kinases

　　There are more than 600 receptor-like kinases (RLKs) in Arabidopsis that locate on the surface of cells to perceive and transduce chemical signals into cells, regulating downstream gene expression and responding to a variety of biotic or abiotic stimuli. So far, biological functions have been defined for only a handful of RLKs that play crucial roles in many physiological processes in plant. My research is focusing on revealing the functions of these RLKs. Preliminary studies showed that gene members of a couple of RLK subfamilies regulate anther and ovary development, and zygotic embryogenesis, which is under intensive investigation.

　?。?）植物生殖生物學(xué)。被子植物雙受精是一個(gè)復(fù)雜的過程，一個(gè)精細(xì)胞與卵細(xì)胞融合形成合子，發(fā)育成胚胎，是下一代植物的雛形；另一個(gè)精細(xì)胞與中央細(xì)胞融合形成胚乳，為胚胎發(fā)育提供營(yíng)養(yǎng)。雙受精的成敗關(guān)系到植物種群的延續(xù)，同時(shí)也關(guān)系到絕大部分農(nóng)作物的產(chǎn)量與質(zhì)量。實(shí)驗(yàn)室目前的工作主要是利用模式植物擬南芥研究雌雄生殖器官以及性細(xì)胞發(fā)育調(diào)控的分子機(jī)理，以及早期胚胎發(fā)育調(diào)控的信號(hào)途徑。

　　Plant Reproductive Biology

　　Double fertilization is a very complex biological process of angiosperms. After transferred into embryo sac by pollen tube, one sperm cell fuses with the egg cell, forming the zygote that will develop into the embryo, and the other sperm cell fuses with the center cell to generate the endosperm that provides nutrients for embryo development. Successful double fertilization is critical for the survival and development of every species, and is also crucial for the quantity and quality of the production of many crops. Plants have complex regulatory systems to regulate the development of sexual organs to achieve successful double fertilization and embryogenesis. My current research is focusing on those genes involved in anther, ovule and embryo development.

　　項(xiàng)目成果

　　實(shí)驗(yàn)室得到國(guó)家自然科學(xué)基金委員會(huì)、教育部、科技部和蘭州大學(xué)的經(jīng)費(fèi)支持。

　　1、主持項(xiàng)目：

　　國(guó)家自然科學(xué)基金面上項(xiàng)目《擬南芥富含亮氨酸重復(fù)類受體激酶調(diào)控合子胚胎發(fā)育的分子機(jī)理》（No.31070283）

　　國(guó)家自然科學(xué)基金面上項(xiàng)目《擬南芥珠被發(fā)育的信號(hào)網(wǎng)絡(luò)與調(diào)控機(jī)理》（No.31270229）

　　國(guó)家自然科學(xué)基金面上項(xiàng)目《PzIPT1在擬南芥精細(xì)胞中表達(dá)的分子機(jī)理研究》（No.31471402）

　　教育部新世紀(jì)優(yōu)秀人才支持計(jì)劃項(xiàng)目《受體激酶調(diào)控花藥發(fā)育的分子機(jī)理》（No. NCET-12-0249）

　　教育部科學(xué)技術(shù)項(xiàng)目《受體激酶SERKs調(diào)控?cái)M南芥胚胎發(fā)育的信號(hào)通路》（No.113058A）

　　2、參加項(xiàng)目：

　　國(guó)家自然科學(xué)基金重大研究計(jì)劃重點(diǎn)項(xiàng)目《一類植物特有的轉(zhuǎn)錄因子TCP在油菜素內(nèi)酯生物合成及信號(hào)轉(zhuǎn)導(dǎo)中的調(diào)控機(jī)理》（No.90917019）

　　教育部“長(zhǎng)江學(xué)者和創(chuàng)新團(tuán)隊(duì)發(fā)展計(jì)劃”創(chuàng)新團(tuán)隊(duì)項(xiàng)目《植物多重抗逆的分子機(jī)理》（Nos.IRT0924, IRT_13R25）

　　科技部重大科學(xué)研究計(jì)劃課題《植物蛋白的修飾的重要過程與調(diào)控機(jī)理》（No.2011CB9154001）

　　榮譽(yù)、獲獎(jiǎng)

　　教育部新世紀(jì)優(yōu)秀人才支持計(jì)劃（2012）

 

蘭州大學(xué)研究生導(dǎo)師：向云

　　學(xué)習(xí)經(jīng)歷

　　1997.9--2001.7：甘肅農(nóng)業(yè)大學(xué)，學(xué)士

　　2001.9--2004.7：甘肅農(nóng)業(yè)大學(xué)，碩士

　　2004.9--2007.7：北京師范大學(xué)，博士

　　2008.5--2011.8：蘭州大學(xué)，在職博士后

　　2010.2--2011.8：美國(guó)杜克大學(xué)，訪問學(xué)者

　　工作經(jīng)歷

　　2007.7--2013.5：蘭州大學(xué)，副教授

　　2013.5--至今：蘭州大學(xué)，教授

　　教學(xué)及指導(dǎo)研究生情況

　　發(fā)表論文及專著

　　*代表通訊作者，#代表共同第一作者

　　[1] Yue Niu*, Dong Qian, Baiyun Liu, Jianchao Ma, Dongshi Wan, Xinyu Wang, Wenliang He, Yun Xiang*. ALA6, a P4-type ATPase, Is Involved in Heat Stress Responses in Arabidopsis thaliana. Frontiers in Plant Science, 2017, https://doi.org/10.3389/fpls.2017.01732.

　　[2] Hui Su*, Hualing Feng, Xiaoting Chao, Xia Ding, Qiong Nan, Chenxi Wen, Huidong Liu, Sinuo Liu, Yun Xiang*, Wenzhe Liu*, Fimbrins 4 and 5 Act Synergistically During Polarized Pollen-tube Growth to Ensure Fertility in Arabidopsis. Plant and Cell Physiology, 2017, https://doi.org/10.1093/pcp/pcx138.

　　[3] Jingen Zhu#, Qiong Nan#, Tao Qin#, Dong Qian, Tonglin Mao, Shunjie Yuan, Xiaorong Wu, Yue Niu, Qifeng Bai, Lizhe An, Yun Xiang*, Higher-ordered Actin Structures Remodeled by Arabidopsis ACTIN-DEPOLYMERIZING FACTOR5 Are Important for Pollen Germination and Pollen Tube Growth. Molecular Plant, 2017, 10: 1065-1081.

　　[4] Qiong Nan#, Dong Qian#, Yue Niu, Yongxing He, Shaofei Tong, Zhimin Niu, Jianchao Ma, Yang Yang, Lizhe An, Dongshi Wan*, Yun Xiang*, Plant Actin-depolymerizing Factors Possess Opposing Biochemical Properties Arising from Key Amino Acid Changes Throughout Evolution. Plant Cell, 2017, 29(2): 395-408. (Highlighted paper by Science Editor in “In Brief” )

　　Jennifer Lockhart, Loose-Knit Family: Tracing the Evolution of Actin-Depolymerizing Factors That Sever or Join the Actin Cytoskeleton. Plant Cell, 2017, 29 (2): 200-201, DOI: https://doi.org/10.1105/tpc.17.00088.

　　[5] Jiangtao Liu, Yuelong Zhou, Changxin Luo, Yun Xiang, Lizhe An*, De Novo Transcriptome Sequencing of Desert Herbaceous Achnatherum splendens (Achnatherum) Seedlings and Identification of Salt Tolerance Genes. Genes, 2016, 23: 7(4): 12.

　　[6] Hui Wang, Shengcheng Han, Wei Siao, Chunqing Song, Yun Xiang, Xiaorong Wu, Pengyu Cheng, Hongjuan Li, Ján Jásik, Karol Mi?ieta, Ján Turňa, Boris Voigt, Franti?ek Balu?ka, Jin Liu, Yingdian Wang, Heping Zhao*, Arabidopsis Synaptotagmin 2 Participates in Pollen Germination and Tube Growth and Is Delivered to Plasma Membrane via Conventional Secretion. Molecular Plant, 2015, 8(12):1737-1750.

　　[7] Dong Qian, Qiong Nan, Yang Yang, Hui Li, Yuelong Zhou, Jingen Zhu, Qifeng Bai, Pan Zhang, Lizhe An, Yun Xiang*, Gelsolin-Like Domain 3 Plays Vital Roles in Regulating the Activities of the Lily Villin/Gelsolin/Fragmin Superfamily. PLoS One, 2015, 10(11): e0143174.

　　[8] Jingen Zhu, Xiaorong Wu, Shunjie Yuan, Dong Qian, Qiong Nan, Lizhe An, Yun Xiang* (2014) Annexin5 Plays a Vital Role in Arabidopsis Pollen Development via Ca2+-Dependent Membrane Trafficking. PLoS One, 2014, 9(7): e102407.

　　[9] Jingen Zhu, Shunjie Yuan, Guo Wei, Dong Qian, Xiaorong Wu, Honglei Jia, Mengyuan Gui, Wenzhe Liu, Lizhe An*, Yun Xiang*, Annexin5 is Essential for Pollen Development in Arabidopsis. Molecular Plant, 2014, 7(4): 751-754.

　　[10] Honglei Jia, Jisheng Li, Jingen Zhu, Tingting Fan, Dong Qian, Yuelong Zhou, Jue Wang, Haiyun Ren, Yun Xiang*, Lizhe An*, Arabidopsis CROLIN1, a Novel Plant Actin-binding Protein, Functions in Cross-linking and Stabilizing Actin Filaments. Journal of Biological Chemisty, 2013, 288: 32277-32288.

　　[11] Tingting Fan, Huanhuan Zhai, Wenwei Shi, Jue Wang, Honglei Jia, Yun Xiang*, Lizhe An*, Overexpression of Profilin 3 Affects Cell Elongation and F-actin Organization in Arabidopsis thaliana. Plant Cell Reports, 2013, 32(1): 149-160.

　　[12] Binyun Ma, Dong Qian, Qiong Nan, Chang Tan, Lizhe An*, Yun Xiang*, Arabidopsis V-ATPase B Subunits Are Involved in Actin Cytoskeleton Remodeling via Binding to, Bundling and Stabilizing F-actin. Journal of Biological Chemisty, 2012, 287: 19008-19017.

　　[13] Jue Wang, Dong Qian, Tingting Fan, Honglei Jia, Lizhe An*, Yun Xiang*, Arabidopsis Actin Capping Protein (AtCP) Subunits Have Different Expression Patterns, and Downregulation of AtCPB Confers Increased Thermotolerance of Arabidopsis after Heat Shock Stress. Plant Science, 2012, 193: 110-119.

　　[14] Shanjin Huang, Yun Xiang, Haiyun Ren. (2011). Actin-binding Proteins and Actin Dynamics in Plant Cells. In The Plant Cytoskeleton, 2011, pp. 57-80. Springer New York.

　　[15] Binyun Ma, Yun Xiang, Lizhe An*, Structural Bases of Physiological Functions and Roles of the Vacuolar H+-ATPase. Cellular Signalling, 2011, 23: 1244-1256.

　　[16] Ting Wang#, Yun Xiang#, Jian Hou, Haiyun Ren*, ABP41 is Involved in the Pollen Tube Development via Fragmenting Actin Filaments. Molecular Plant, 2008, 1(6): 1048-1055.

　　[17] Yun Xiang, Xi Huang, Ting Wang, Yan Zhang, Qinwen Liu, Patrick J Hussey, Haiyun Ren*, ACTIN BINDING PROTEIN29 from Lilium Pollen Plays an Important Role in Dynamic Actin Remodeling. Plant Cell, 2007, 19(6): 1930-1946.

　　[18] Haiyun Ren*, Yun Xiang, The Function of Actin-binding Proteins in Pollen Tube Growth. Protoplasma, 2007, 230(3-4): 171-182.

　　研究方向

　　微絲骨架（actin cytoskeleton）是遍布于一切真核細(xì)胞中的三維網(wǎng)狀結(jié)構(gòu)，占植物總蛋白的15-20%，在維持細(xì)胞形態(tài)、參與細(xì)胞運(yùn)動(dòng)、胞質(zhì)分裂和極性建立等重要細(xì)胞生理活動(dòng)中起著決定性的作用。微絲骨架的動(dòng)態(tài)變化是其行使各種生理功能的基礎(chǔ)，而該過程則直接受到諸多微絲結(jié)合蛋白和不同信號(hào)分子的調(diào)控。本課題組以模式作物擬南芥為材料，主要開展如下研究工作：

　　1. 探索植物特有的、功能未知的微絲結(jié)合蛋白；

　　2. 微絲骨架參與植物花粉管極性生長(zhǎng)的分子機(jī)理；

　　3. 微絲骨架參與植物響應(yīng)各種非生物脅迫的分子機(jī)理；

　　4. 植物抗逆信號(hào)轉(zhuǎn)導(dǎo)（鈣離子）。

　　項(xiàng)目成果

　　1. 國(guó)家自然科學(xué)基金-優(yōu)秀青年科學(xué)基金項(xiàng)目，31722005，植物細(xì)胞骨架，2018/01-2020/12，在研，主持

　　2. 國(guó)家自然科學(xué)基金-面上項(xiàng)目，31670180，擬南芥微絲解聚因子第三亞家族成員生理生化功能研究，2017/01-2020/12，在研，主持

　　3. 國(guó)家自然科學(xué)基金-面上項(xiàng)目，31470283，擬南芥微絲交聯(lián)蛋白CROLINs調(diào)控花粉管生長(zhǎng)的分子機(jī)理研究，2015/01-2018/12，在研，主持

　　4. 教育部"新世紀(jì)優(yōu)秀人才支持計(jì)劃"，NCET-13-0264，植物細(xì)胞骨架，2014/01-2015/12，已結(jié)題，主持

　　5. 國(guó)家自然科學(xué)基金-面上項(xiàng)目，31270326，擬南芥液泡氫ATP酶B亞基不同異形體的生理生化功能及作用機(jī)理研究，2013/01-2016/12，已結(jié)題，主持

　　6. 甘肅省杰出青年基金，2013GS10064，微絲骨架參與植物響應(yīng)干旱和高鹽脅迫分子機(jī)理研究，2013/01-2015/12，已結(jié)題，主持

　　7. 國(guó)家自然科學(xué)基金-青年科學(xué)基金，30800079，擬南芥膜聯(lián)蛋白annexin5調(diào)控花粉管極性生長(zhǎng)的分子機(jī)制研究，2009/01-2011/12，已結(jié)題，主持

　　榮譽(yù)、獲獎(jiǎng)

　　1. 國(guó)家優(yōu)秀青年基金（2017）

　　2. 教育部"新世紀(jì)優(yōu)秀人才支持計(jì)劃"（2013）

　　3. 甘肅省杰出青年基金（2013）

 

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