大連醫(yī)科大學基礎醫(yī)學院導師:馬郁芳

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大連醫(yī)科大學基礎醫(yī)學院導師:馬郁芳

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大連醫(yī)科大學基礎醫(yī)學院導師:馬郁芳 正文

[導師姓名]
馬郁芳

[所屬院校]
大連醫(yī)科大學

[基本信息]
導師姓名:馬郁芳
性別:
人氣指數(shù):1026
所屬院校:大連醫(yī)科大學
所屬院系:基礎醫(yī)學院
職稱:教授
導師類型:
招生專業(yè):
研究領域:微生物生物化學與分子生物學



[通訊方式]
辦公電話:0411-86110338
電子郵件:yufang_ma@hotmail.com

[個人簡述]
馬郁芳, 博士,教授,碩士生及博士生導師?,F(xiàn)任大連醫(yī)科大學基礎醫(yī)學院生物化學教研室。遼寧省新世紀百千萬人才工程百層次人選,遼寧省優(yōu)秀教師。

[科研工作]
承擔的國家級項目:(近5年)1、國家自然科學基金 (81573469):結核分枝桿菌GlmU乙?;D移酶抑制劑的作用機制研究及抑菌效果評價 (2016.1. - 2019.12.,54.00 萬),排名1;2、大連醫(yī)科大學首批 “英才工程” 優(yōu)秀人才支持計劃 (第二層次),結核分枝桿菌細胞壁合成酶和細胞壁蛋白功能研究、2013/04 - 2016/03、排名1;3、國家重點基礎研究發(fā)展計劃、動物重要病原菌功能基因組與分子致病機理研究、課題3:病原菌表面多糖的結構與功能、2012/01 - 2016/12、排名2;4、高等學校博士學科點專項科研基金項目、結核分枝桿菌UDP-N-乙酰烯醇丙酮酸葡糖胺還原酶的結構與功能研究、2012/01 - 2014/12、排名1;5、國家自然科學基金面上項目、結核分枝桿菌磷酸葡糖胺變位酶 (GlmM) 的功能研究、2010/01 - 2012/12、排名1;
代表性論文(近5年):例:作者、文章題目、雜志名稱(影響因子)、卷期、頁碼1.Guoying Deng, Fei Zhang, Shufeng Yang, Jian Kang, Shanshan Sha, Yufang Ma. Mycobacterium tuberculosis Rv0431, a mannosylated protein, enhanced the mycobacterial survival and modulated cytokines production of RAW 264.7 macrophages. Microbial Pathogenesis (1.888) 2016, 100: 285-292.
2.Liming Xu, Lei Qian, Jian Kang, Shanshan Sha, Xin Yi, Shen Lu, Yufang Ma. Down-regulation of N-acetylglucosamine-1-phosphate transferase (WecA) enhanced the sensitivity of Mycobacterium smegmatis against rifampin. Journal of Applied Microbiology (2.156) 2016, 121: 966-972.
3.Qiulong Yan, Song Cui, Changming Chen, Shenghui Li, Shanshan Sha, Xianyao Wan, Yi Xin, Yufang Ma. Metagenomic analysis of sputum microbiome as a tool towards culture-independent pathogen detection of patients with ventilator-associated pneumonia. American Journal of Respiratory and Critical Care Medicine (13.118) 2016, 195(5): 636-639.
4.Xiaofeng Yao, Shanshan Sha, Yuexia Wang, Xiance Sun, Jun Cao, Jian Kang, Liping Jiang, Min Chen, Yufang Ma. Perfluorooctane sulfonate induces autophagy dependent apoptosis through Spinster 1-mediated lysosomal-mitochondrial axis and impaired mitophagy. Toxicological Sciences (3.88) 2016, 153(1): 198-211.
5.Xiaofeng Yao and Yufang Ma. Chapter 9. Organic pollutant perfluorooctane sulfonate-induced lysosomal membrane permeabilization blocks autophagy flux in human hepatoma cells. In: Autophagy: Cancer, Other Pathologies, Inflammation, Immunity, Infection, and Aging. Volume 9. Human Diseases and Autophagosome (1st edition) (Edited by Hayat MA). Academic Press (2016), ISBN 978-0128029367. pp176-184.
6.Shanshan Sha, Xiaoxia Shi, Liming Xu, Jiabin Wen, Yi Xin and Yufang Ma. Viability, morphology and proteome of M. smegmatis MSMEG_0319 knockout strain. Proteomics (4.079) 2016, 16: 1090-1099.
7.Xiaoxia Shi, Shanshan Sha, Likun Liu, Xin Li, Yufang Ma. A microtiter plate assay for high-throughput screening of Mycobacterium tuberculosis dTDP-d-glucose-4, 6-dehydratase inhibitors. Analytical Biochemistry (2.243) 2016, 498: 53-58.
8.Jianjun Liu, Qiulong Yan, Fuwen Luo, Dong Shang, Dachang Wu, Haiquan Zhang, Xueqi Shang, Xiaoli Kang, Meyiah Abdo, Beibei Liu, Yufang Ma and Yi Xin. Acute cholecystitis associated with infection of Enterobacteriaceae from gut microbiota. Clinical Microbiology and Infection (4.575) 2015, 21(9):851.e1-9.
9.Shufeng Yang, Fei Zhang, Jian Kang, Wenli Zhang, Guoying Deng, Yi Xin, Yufang Ma. Mycobacterium tuberculosis Rv1096 protein: gene cloning, protein expression,and peptidoglycan deacetylase activity. BMC Microbiology (2.976) 2014, 14:174.
10.Xiao-Feng Yao, Jun Cao, Li-Ming Xu, Xian-Ce Sun, Jian Kang, Guang Yang, Li-Ping Jiang, Cheng-Yan Geng, Chuan-Zhou Gao, Lai-Fu Zhong, Yu-Fang Ma. Perfluorooctane sulfonate blocked autophagy flux and induced lysosome membrane permeabilization in HepG2 cells. Food and Chemical Toxicology (2.61) 2014, 67:96-104.
11.Juanjuan Qiu, Yufang Ma, Lawrence Owusu, Tao Jiang, Yi Xin. Functional analysis of serine acetyltransferase from Mycobacterium smegmatis. Journal of Basic Microbiology (1.822) 2014, 54:670-677.
12.Liming Xu, Dongting Wu, Liang Liu, Qi Zheng, Yu Song, Li Ye, Shanshan Sha, Jian Kang, Yi Xin, Yufang Ma. Characterization of mycobacterial UDP-N-acetylglucosamine enolpyruvyle transferase (MurA). Research in Microbiology (2.828) 2014, 165:91-101.
13.Huajun Li, Jya-Wei Cheng, Hui-Yuan Yu, Yi Xin, Li Tang and Yufang Ma. Effect of the antimicrobial peptide D-Nal-Pac-525 on the growth of Streptococcus mutans and its biofilm formation. Journal of Microbiology and Biotechnology (1.32), 2013, 23(8):1070-1075.
14.Jian Kang, Liming Xu, Shufeng Yang, Wendan Yu, Shuo Liu, Yi Xin and Yufang Ma. Effect of phosphoglucosamine mutase on biofilm formation and antimicrobial susceptibilities in M. smegmatis glmM gene knockdown strain. PLoS One (3.534), 2013, 8(4): e61589.
15.Juanjuan Qiu, Daiqing Wang, Yufang Ma, Tao Jiang, Yi Xin. Identification and characterization of serine acetyltransferase encoded by the Mycobacterium tuberculosis Rv2335 gene. International Journal of Molecular Medicine (1.88), 2013, 31(5):1229-1233.

[教育背景]
1997年09月 - 2000年06月,理學博士 大連醫(yī)科大學;
1991年01月 - 1994年05月,理學碩士 美國 North Dakota State University;
1984年09月 - 1987年07月,理學碩士 北京師范大學;
1980年09月 - 1984年07月,理學學士 河南師范大學。
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