大連醫(yī)科大學(xué)基礎(chǔ)醫(yī)學(xué)院導(dǎo)師:李連宏
大連醫(yī)科大學(xué)基礎(chǔ)醫(yī)學(xué)院導(dǎo)師:李連宏內(nèi)容如下,更多考研資訊請關(guān)注我們網(wǎng)站的更新!敬請收藏本站,或下載我們的考研派APP和考研派微信公眾號(里面有非常多的免費(fèi)考研資源可以領(lǐng)取,有各種考研問題,也可直接加我們網(wǎng)站上的研究生學(xué)姐微信,全程免費(fèi)答疑,助各位考研一臂之力,爭取早日考上理想中的研究生院校。)
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大連醫(yī)科大學(xué)基礎(chǔ)醫(yī)學(xué)院導(dǎo)師:李連宏 正文
[導(dǎo)師姓名]李連宏
[所屬院校]
大連醫(yī)科大學(xué)
[基本信息]
導(dǎo)師姓名:李連宏
性別:
人氣指數(shù):1457
所屬院校:大連醫(yī)科大學(xué)
所屬院系:基礎(chǔ)醫(yī)學(xué)院
職稱:教授
導(dǎo)師類型:博導(dǎo)
招生專業(yè):
研究領(lǐng)域:乳腺癌干細(xì)胞發(fā)生機(jī)制及其靶向治療
[通訊方式]
辦公電話:86110050
電子郵件:lilianhong917@126.com
[個人簡述]
李連宏,男,醫(yī)學(xué)博士、病理學(xué)與法醫(yī)學(xué)雙博導(dǎo),二級教授,現(xiàn)任大連醫(yī)科大學(xué)組織部部長,國務(wù)院政府特殊津貼獲得者,遼寧省教學(xué)名師,大連市優(yōu)秀教師,大連市優(yōu)秀專家,國家科技部和教育部及省市多項專家,兼任《臨床與實(shí)驗(yàn)病理學(xué)雜志》等多個雜志編委。
[科研工作]
承擔(dān)的國家級項目:(近5年)1. 國家自然科學(xué)基金miR-34a在乳腺癌干細(xì)胞自我更新過程中的調(diào)節(jié)機(jī)制 81272430 2013.1-2016.12 85萬 主持人
代表性論文(近5年):例:作者、文章題目、雜志名稱(影響因子)、卷期、頁碼 SCI收錄1.Zhang C, Lu Y, Li Q, Mao J, Hou Z, Yu X, Fan S, Li J, Gao T, Yan B, Wang B, Song B, Li L.(通訊作者),Salinomycin suppresses TGF-beta 1-induced epithelial-to-mesenchymal transition in MCF-7 human breast cancer cells,Chem Biol Interact. 2016 Mar 25248:74-81(影響因子2.618)
2.Zhang J, Liu D, Feng Z, Mao J, Zhang C, Lu Y, Li J, Zhang Q, Li Q, Li L.(通訊作者),MicroRNA-138 modulates metastasis and EMT in breast cancer cells by targeting vimentin,Biomed Pharmacother. 2016 Feb77:135-41(影響因子2.326)
3.Gao T, Li JZ, Lu Y, Zhang CY, Li Q, Mao J, Li LH.(通訊作者),The mechanism between epithelial mesenchymal transition in breast cancer and hypoxia microenvironment,Biomed Pharmacother. 2016 May80:393-405(影響因子2.326)
4.Zhang F, Li L, Yang X, Wang B, Zhao J, Lu S, Yu X.(第2作者),Expression and activation of EGFR and STAT3 during the multistage carcinogenesis of intrahepatic cholangiocarcinoma induced by 3'-methyl-4 dimethylaminoazobenzene in rats.J Toxicol Pathol.2015 Apr28(2):79-87(影響因子0.848)
5.Zhang F, Yang X, Li L, Sun L, Wang BO, Yu X.(第3作者),Epidermal growth factor receptor expression and gene copy number analysis in gastric carcinoma samples from Chinese patients,Oncol Lett. 2016 Jan11(1):173-181(影響因子1.482)
6.Xiang D, Zheng C, Zhou SF, Qiao S, Tran PH, Pu C, Li Y, Kong L, Kouzani AZ, Lin J, Liu K, Li L, Shigdar S, Duan W.(第12作者),Superior Performance of Aptamer in Tumor Penetration over Antibody: Implication of Aptamer-Based Theranostics in Solid Tumors.Theranostics. 2015 Jul 25(10):1083-97(影響因子8.854)
7.Ma W, Xiao GG, Mao J,Lu Y, Song B, Wang L, Fan S, Hou Z, Li J, Wang B, Xu F, Liu Q, Li L.(通訊作者),Dysregulation of the miR-34a-SIRT1 axis inhibits breast cancer stemness. Oncotarget. 20153. (影響因子6.791)
8.Le Kang, Jun Mao, Yajun Tao, Bo Song,Wei Ma, Ying Lu, Lijing Zhao, Jiazhi Li,Bao xue Yang and Lianhong Li.(通訊作者), MiR-34a Suppresses the Breast Cancer Stem Cell-like Characteristics by Downregulating Notch1 Pathway. Cancer Science.2015. (影響因子3.534)
9. Lu Y, Ma W, Mao J, Yu X, Hou Z, Fan S, Song B, Wang H, Li J, Kang L, Liu P, Liu Q, Li L.(通訊作者),Salinomycin exerts anticancer effects on human breast carcinoma MCF-7 cancer stem cells via modulation of Hedgehog signaling. Chem Biol Interact. 201525:100-107. (影響因子2.982)
10. Wang L, Duan W, Kang L, Mao J, Yu X, Fan S, Li L, Tao Y. (通訊作者),Smoothened activates breast cancer stem-like cell and promotes tumorigenesis and metastasis of breast cancer. Biomed Pharmacother 201468(8):1099-1104. (影響因子2.108)
11. J Mao, S Fan, W Ma, P Fan, B Wang, J Zhang, H Wang, B Tang, Q Zhang, X Yu, L Wang, B Song and L Li. (通訊作者),Roles of Wnt/b-catenin signaling in the gastric cancer stem cells proliferation and salinomycin treatment. Cell Death & Disease 2014 5: e1039. (影響因子5.177)
12. Lin song, Jun Mao, Jun Zhang, Ibrahim MM, Lianhong Li,Jianwu Tang. (通訊作者),Annexin A7 and its binding protein galectin-3 influence mouse hepatocellular carcinoma cell line in vitro. Biomedicine & Pharmacotherapy 201368(3):377-384. (影響因子2.108)13. Fan P, Fan S, Wang H, Mao J, Shi Y, Ibrahim MM, Ma W, Yu X, Hou Z, Wang B, Li L. (通訊作者),Genistein decreases the breast cancer stem-like cell population through Hedgehog pathway. Stem Cell Res Ther. 2013,4(6):146. (影響因子4.634)
14. Jin Y, Mao J, Wang H, Hou Z, Ma W, Zhang J, Wang B, Huang Y, Zang S, Tang J, Li L. (通訊作者),Enhanced tumorigenesis and lymphatic metastasis of CD133+ hepatocarcinoma ascites syngeneic cell lines mediated by JNK signaling pathway in vitro and in vivo. Biomed Pharmacother. 2013 ,67(4):337-45. (影響因子2.108)
15. Mao J, Song B, Shi Y, Wang B, Fan S, Yu X, Tang J, Li L. (通訊作者),ShRNA targeting Notch1 sensitizes breast cancer stem cell to paclitaxel. Int J Biochem Cell Biol. 2013 ,45(6):1064-73. (影響因子4.240)
16. Li L, Xiao B, Tong H, Xie F, Zhang Z, Xiao GG. (第1作者),Regulation of breast cancer tumorigenesis and metastasis by miRNAs. Expert Rev Proteomics. 2012,9(6):615-25. (影響因子3.542)
17. Tao Y, Mao J, Zhang Q, Li L. (通訊作者), Overexpression of Hedgehog signaling molecules and its involvement in triple-negative breast cancer. Oncol Lett. 2011 ,2(5):995-1001. (影響因子0.987)
18. Yan M, Zhang Y, He B, Xiang J, Wang ZF, Zheng FM, Xu J, Chen MY, Zhu YL, Wen HJ, Wan XB, Yue CF, Yang N, Zhang W, Zhang JL, Wang J, Wang Y, Li LH, Zeng YX, Lam EW, Hung MC, Liu Q. (第18作者),IKK alpha restoration via EZH2 suppression induces nasopharyngeal carcinoma differentiation. Nat Commun.2014,5:3661. (影響因子10.742)
19. Shigdar S, Qiao L, Zhou SF, Xiang D, Wang T, Li Y, Lim LY, Kong L, Li L, Duan W.(通訊作者),RNA aptamers targeting cancer stem cell marker CD133. Cancer Lett. 2013, 330(1):84-95. (影響因子5.016)
20. Shigdar S, Qian C, Lv L, Pu CW, Li Y, Li LH, Marappan M, Lin J, Wang LF, Duan W.(第6作者) ,The Use of Sensitive Chemical Antibodies for Diagnosis: Detection of Low Levels of Epcam in Breast Cancer. PLOS ONE.2013, 8(2): e57613. (影響因子3.534)
21.Chu Wanjiang,Zhuang Engui,Wang Honghai,Xu Zhuping,Bai Canming,Wang Jian and Li Lianhong,(通訊作者), Construction and application of high quality medical video teaching resources.Frontier and future development of information technology in medicine and education.2013,3:2013-2021
[教育背景]
1999年9月-2002年7月 醫(yī)學(xué)博士 大連醫(yī)科大學(xué);
1988年9月-1991年7月 醫(yī)學(xué)碩士 白求恩醫(yī)科大學(xué);
1979年9月-1984年 7月 醫(yī)學(xué)學(xué)士 大連醫(yī)科大學(xué)。
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