大連醫(yī)科大學(xué)第二臨床學(xué)院導(dǎo)師:田曉峰
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大連醫(yī)科大學(xué)第二臨床學(xué)院導(dǎo)師:田曉峰 正文
[導(dǎo)師姓名]田曉峰
[所屬院校]
大連醫(yī)科大學(xué)
[基本信息]
導(dǎo)師姓名:田曉峰
性別:
人氣指數(shù):2306
所屬院校:大連醫(yī)科大學(xué)
所屬院系:第二臨床學(xué)院
職稱:教授
導(dǎo)師類型:博導(dǎo)
招生專業(yè):醫(yī)療管理、普通外科學(xué)
研究領(lǐng)域:普外甲狀腺、乳腺外科及重癥病人多器官功能衰竭發(fā)病機(jī)制及保護(hù)的研究。
[通訊方式]
電子郵件:txfdl@dmu.edu.cn
[個(gè)人簡(jiǎn)述]
田曉峰,1963年生人,醫(yī)學(xué)博士,二級(jí)教授,博士生導(dǎo)師,校長(zhǎng)助理,農(nóng)工民主黨黨員。
遼寧省特聘教授,遼寧省百千萬(wàn)人才百人層次,遼寧省重點(diǎn)學(xué)科帶頭人,遼寧省優(yōu)秀人才支持計(jì)劃獲得者。大連市首批科技領(lǐng)軍人才、大連市政府特貼、大連市勞動(dòng)模范、大連市十大杰出青年獲得者。中華醫(yī)學(xué)會(huì)遼寧省外科分會(huì)常委、急腹癥學(xué)組副組長(zhǎng),大連醫(yī)學(xué)會(huì)常務(wù)理事,大連醫(yī)師學(xué)會(huì)理事。先后獲得國(guó)家科技部863課題1項(xiàng)、國(guó)家自然科學(xué)基金3項(xiàng),以及省市各類課題20余項(xiàng)。發(fā)表文章110余篇,SCI收錄51篇,總影響因子130。主編衛(wèi)生部專科規(guī)劃教材《外科學(xué)》和《實(shí)用普通外科手術(shù)學(xué)》等著作,參編本科規(guī)劃教材《急癥醫(yī)學(xué)》及《現(xiàn)代外科理論與實(shí)踐》等大型專著。獲得國(guó)家專利技術(shù)1項(xiàng),省科技進(jìn)步二等獎(jiǎng)1項(xiàng),三等獎(jiǎng)2項(xiàng),大連市科技進(jìn)步一等獎(jiǎng)2項(xiàng)。培養(yǎng)畢業(yè)博、碩士研究生60余人?,F(xiàn)任大連醫(yī)科大學(xué)學(xué)報(bào)副主編,Would Journal of Hepatoloy、中華消化外科雜志、中國(guó)普外基礎(chǔ)與臨床雜志、世界華人消化雜志、中國(guó)醫(yī)師進(jìn)修雜志、中國(guó)實(shí)用外科雜志、中國(guó)普外基礎(chǔ)與臨床雜志、醫(yī)學(xué)與哲學(xué)雜志等多個(gè)專業(yè)雜志的編委。
[科研工作]
在研項(xiàng)目:1、2013年國(guó)家自然科學(xué)基金面上項(xiàng)目: Mir34a調(diào)控Sirt1-P66shc通路在腸缺血再灌注多器官損傷中的防止靶點(diǎn)研究(81372037)(2013 -2017) 70萬(wàn)
2、2012 國(guó)家教育部博士學(xué)科點(diǎn)專項(xiàng)基金: Sirt1通路在腸缺血再灌注多器官損傷發(fā)病機(jī)制中的核心作用及其防治靶點(diǎn)的研究 (20122105110001)(2012-2015) ,12萬(wàn)元
3、2012國(guó)家自然科學(xué)基金: p66shc通路在腸缺血再灌注多器官損傷發(fā)病機(jī)制中的作用及其防治靶點(diǎn)的研究 (81171850) 58萬(wàn)元
代表文章(責(zé)任作者):1、Wang G, Yao J, Li Z, Zu G, Feng D, Shan W, Li Y, Hu Y, Zhao Y, Tian X*. miR-34a-5p inhibition alleviates intestinal ischemia/reperfusion induced ROS accumulation and apoptosis via activation of SIRT1 signaling. Antioxid Redox Signal. 2016, 24(17): 961-973. IF 7.4
2、Wei Xu, Yang Lu, Jihong Yao, Zhenlu Li, Zhao Chen, Guangzhi Wang, Huirong Jing, Xinyuan Zhang, Mingzhu Li, Jinyong Peng, Xiaofeng Tian*. Novel Role of Resveratrol: Suppression of HMGB1 Nucleocytoplasmic Translocation by the Up-Regulation of SIRT1 in Sepsis-Induced Liver Injury. Shock. 2014, 42(5): 440-447. IF 2.87
3、Zhe Fan, Huirong Jing , Jihong Yao , Yang Li, Xiaowei Hu, Huizhu Shao, Gang Shen, Jiyong Pan, Fuwen Luo, Xiaofeng Tian*. The protective effects of curcumin on experimental acute liver lesion induced by intestinal ischemia reperfusion through inhibiting the pathway of NF-κ B in a rat model. Oxidative Medicine and Cellular Longevity. 2014: 191624. IF 3.39
4、Guangzhi Wang, Zhao Chen, Feng Zhang, Huirong Jing, Wei Xu, Shili Ning, Zhenlu Li, Kexin Liu, Jihong Yao*, Xiaofeng Tian*. Blockade of PKCβ protects against remote organ injury induced by intestinal ischemia and reperfusion via a p66shc-mediated mitochondrial apoptotic pathway. Apoptosis, 2014, 19(9): 1342-1353. IF 3.949
5、Feng Zhang, Yan Hu, Xiaomei Xu, Xiaohan Zhai, Guangzhi Wang, Shili Ning, Jihong Yao, Xiaofeng Tian*. Icariin protects against intestinal ischemia/reperfusion injury through activation of SIRT1/FOXO3 pathway. Journal of Surgical Research, 2015, 194(1): 127-138. IF 2.02
6、Zhao Chen, Guangzhi Wang, Xiaohan Zhai, Yan Hu, Dongyan Gao, Lingfei Ma, Jihong Yao*, Xiaofeng Tian*. Selective Inhibition of Protein Kinase C β2 Attenuates the Adaptor P66Shc-Mediated Intestinal Ischemia-Reperfusion Injury. Cell Death Dis. 2014, 5: e1164. IF 6.044
7、Yan Hu, Feng Zhang, Xiaomei Xu, Xiaohan Zhai, Guangzhi Wang, Zhenhai Ma, Dongyan Gao, Xiaochi Ma, Qing Fan, Kexin Liu, Jihong Yao, Xiaofeng Tian*. SIRT1-mediated inhibition of p66shc expression alleviates liver ischemia/reperfusion injury. Critical Care Medicine, 2014, 42(5): e373-81. IF 6.37
8、Huirong Jing, Jihong Yao, Xingming Liu, Hui Fan, Feng Zhang, Zhenlu Li, Xiaofeng Tian*, Yun Zhou*. Fish-oil emulsion (omega-3 polyunsaturated fatty acids) attenuates acute lung injury induced by intestinal ischemia-reperfusion through Adenosine 5'-monophosphate-activated protein kinase-sirtuin1 pathway. J Surg Res. 2014, 187(1): 252-261. IF 2.121
9、Xiaohan Zhai, Musen Lin, Feng Zhang, Yan Hu, Xiaomei Xu, Yubin Li, Xiaochi Ma, Xiaofeng Tian*, Jihong Yao*. Dietary flavonoid genistein induces Nrf2 and phase II detoxi?cation gene expression via ERKs and PKC pathways and protects against oxidative stress in Caco-2 cells. Mol. Nutr. Food Res. 2012, 57(2): 249-259. IF 4.31
10、Wang GZ, Yao JH, Jing HR, Zhang F, Lin MS, Shi L, Wu H, Gao DY, Liu KX, Tian XF*. Suppression of the p66shc adapter protein by protocatechuic acid prevents the development of lung injury induced by intestinal ischemia reperfusion in mice. J Trauma Acute Care Surg. 2012, 73(5): 1130-1137. IF 1.97
[教育背景]
大連醫(yī)科大學(xué)
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